SCHEMBL5508253

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8266570	0.86	ALOX5 (0.50)	ALOX5NR1H4SHMT2CA12CA9
	SCHEMBL5508079	0.83	CCR2 (0.41)	ALOX5NR1H4RARARARBRARG
	SCHEMBL5508964	0.82	ALOX5 (0.45)	ALOX5NR1H4SHMT2RARARARB
	SCHEMBL5508180	0.81	NPC1 (0.44)	ALOX5RARARARBRARGTP53
	SCHEMBL5505018	0.80	ALOX5 (0.51)	ALOX5TP53LMNAMAOBNPC1
	SCHEMBL10470600	0.79	ALOX5 (0.71)	ALOX5NR1H4SHMT2CA12CA9
	SCHEMBL432850	0.79	ALOX5 (0.71)	ALOX5NR1H4SHMT2CA12CA9
	SCHEMBL5508095	0.78	ALDH1A1 (0.40)	ALOX5NR1H4RARARARBRARG
	SCHEMBL5505713	0.77	ALDH1A1 (0.40)	ALOX5NR1H4RARARARBRARG
	SCHEMBL5504699	0.77	ALDH1A1 (0.44)	ALOX5NR1H4RARARARGLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.