Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | GBA1 | P04062 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967361 | 0.84 | LSS (0.53) | MEN1KMT2AGAASMN1; SMN2MAPT | |
| SCHEMBL9731571 | 0.81 | LMNA (0.50) | LMNANPSR1 | |
| SCHEMBL7660934 | 0.79 | LSS (0.48) | MEN1KMT2AGAASMN1; SMN2GBA1 | |
| SCHEMBL14686825 | 0.78 | LMNA (0.60) | MEN1KMT2AGAASMN1; SMN2HTT | |
| SCHEMBL8203532 | 0.78 | PKM (0.88) | MEN1KMT2AGAASMN1; SMN2RAB9A | |
| SCHEMBL10724066 | 0.78 | PKM (0.88) | MEN1KMT2AGAASMN1; SMN2RAB9A | |
| SCHEMBL4537086 | 0.78 | PKM (0.88) | MEN1KMT2AGAASMN1; SMN2RAB9A | |
| SCHEMBL699639 | 0.78 | PKM (0.88) | MEN1KMT2AGAASMN1; SMN2RAB9A | |
| SCHEMBL565301 | 0.78 | PKM (0.88) | MEN1KMT2AGAASMN1; SMN2RAB9A | |
| SCHEMBL3971438 | 0.78 | PKM (0.88) | MEN1KMT2AGAASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138058-A | Diabetic screening | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |
| EP-0384370-A1 | Substituted pyrimidine derivatives, process for their preparation, and their use as tool | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |