Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARL | Q9H300 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379570 | 0.85 | SIRT6 (0.45) | PARLMAPTCRBNSIRT6ALDH1A1 | |
| SCHEMBL15319189 | 0.75 | CRBN (0.43) | PARLMAPTCRBNSIRT6ALDH1A1 | |
| SCHEMBL9730386 | 0.74 | MMP13 (0.59) | CRBNALDH1A1MEN1KMT2A | |
| SCHEMBL11183530 | 0.74 | MAPT (0.53) | PARLMAPTCRBNSIRT6ALDH1A1 | |
| SCHEMBL9644271 | 0.73 | MMP13 (0.38) | ALDH1A1POLB | |
| SCHEMBL2557016 | 0.73 | SCN2A (0.58) | PARLMAPTSIRT6ALDH1A1SCN2A | |
| SCHEMBL77999 | 0.71 | MEN1 (0.56) | PARLMAPTSIRT6ALDH1A1POLB | |
| SCHEMBL29929946 | 0.71 | MEN1 (0.56) | PARLMAPTSIRT6ALDH1A1POLB | |
| SCHEMBL7549606 | 0.70 | MAPT (0.58) | PARLMAPTSIRT6ALDH1A1SCN2A | |
| SCHEMBL6140639 | 0.70 | MAPT (0.62) | PARLMAPTSIRT6ALDH1A1SCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093499-A | Spirodilactam derivatives | SHELL OIL COMPANY (US) | 1992-03-03 | — | — | US | disclosed |