Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 9/20 | 0.38 |
| ▸ | MMP2 | P08253 | 4/20 | 0.34 |
| ▸ | MMP3 | P08254 | 4/20 | 0.34 |
| ▸ | MMP9 | P14780 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644504 | 0.83 | MMP13 (0.35) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9730839 | 0.75 | MMP13 (0.52) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL515166 | 0.75 | KMT2A (0.48) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9730386 | 0.74 | MMP13 (0.59) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9730368 | 0.72 | MMP13 (0.63) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9773395 | 0.71 | MMP13 (0.43) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9383630 | 0.71 | MMP13 (0.39) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL10392048 | 0.70 | MMP13 (0.50) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9729436 | 0.68 | ALDH1A1 (0.36) | MMP13MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9738296 | 0.68 | NSD2 (0.46) | MMP13MMP2MMP3MMP9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149823-A | Sulfonamide substituted spirodilactams | SHELL OIL COMPANY (US) | 1992-09-22 | — | — | US | disclosed |