SCHEMBL973005

SCHEMBL973005

Cc1ccc2c(c1)C(=O)C=C(O)C2=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.53
MAOB P27338 3/20 0.53
ELANE P08246 2/20 0.52
LCK P06239 1/20 0.51
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
ALDH1A1 P00352 3/20 0.42
CYP3A4 P08684 3/20 0.42
MAPT P10636 3/20 0.42
MAPK1 P28482 3/20 0.42
HPGD P15428 2/20 0.42
KDM4E B2RXH2 2/20 0.42
PTPN22 Q9Y2R2 1/20 0.42
POLB P06746 1/20 0.41
XIAP P98170 1/20 0.41
BCL2 P10415 1/20 0.40
MCL1 Q07820 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30003106 1.00 MAOA (0.53) MAOAMAOBELANELCKCA1
SCHEMBL28591550 0.92 MAOA (0.53) MAOAMAOBELANELCKCA1
SCHEMBL29404998 0.92 MAOA (0.53) MAOAMAOBELANELCKCA1
SCHEMBL30004162 0.80 ESR2 (0.61) MAOAMAOBCA1CA2CA7
SCHEMBL5811756 0.80 ESR2 (0.61) MAOAMAOBCA1CA2CA7
SCHEMBL5820386 0.80 ALDH1A1 (0.61) MAOAMAOBELANELCKCA1
SCHEMBL30002673 0.78 XIAP (0.39) ALDH1A1CYP3A4MAPTMAPK1HPGD
SCHEMBL8993580 0.78 XIAP (0.39) ALDH1A1CYP3A4MAPTMAPK1HPGD
SCHEMBL25379798 0.77 ALDH1A1 (0.52) MAOAMAOBLCKALDH1A1CYP3A4
SCHEMBL9389370 0.77 BCL2 (0.58) MAOAMAOBLCKCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006107827-A1 SKIN BONDING PROCESS CREIGHTON UNIVERSITY (US) 2006-10-12 WO claimed
US-5411675-A Mixtures of aromatic diamines, hydroxynaphthoquinone, acid and silica sol as antiscaling agents SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-05-02 US claimed
WO-2023142518-A1 HYDROXYNAPHTHALENONE-PHENYLBORONIC ACID COMPOUND, PREPARATION METHOD, AND USE 中国药科大学 2023-08-03 WO disclosed
CN-114195814-B Hydroxy naphthalenone-phenylboronic acid compound, preparation method and application 中国药科大学 2023-07-21 CN disclosed
US-11613509-B2 Radical polymerization control agent and radical polymerization control method KAWASAKI KASEI CHEMICALS LTD. (JP) 2023-03-28 US disclosed
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed
CN-114195814-A Hydroxy naphthalenone-phenylboronic acid compound, preparation method and application 中国药科大学 2022-03-18 CN disclosed
CN-110156822-B Naphthol-phenylboronic acid compound and preparation method and application thereof 中国药科大学 2021-07-09 CN disclosed
US-20210122692-A1 RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD KAWASAKI KASEI CHEMICALS LTD. (JP) 2021-04-29 US disclosed
CN-110891980-A Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2020-03-17 CN disclosed
EP-2532390-B1 Pharmaceutical composition for liver diseases. MD BIOALPHA CO LTD (KR) 2016-08-17 EP disclosed
EP-0802730-A1 PESTICIDAL COMPOUNDS BTG INTERNATIONAL LIMITED (GB) 1997-10-29 EP disclosed
WO-1997002271-A1 PESTICIDAL COMPOUNDS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1997-01-23 WO disclosed
EP-0534436-B1 Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel SHINETSU CHEMICAL CO (JP) 1996-08-14 EP disclosed
WO-1996021355-A1 PESTICIDAL COMPOUNDS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1996-07-18 WO disclosed
US-5411675-A Mixtures of aromatic diamines, hydroxynaphthoquinone, acid and silica sol as antiscaling agents SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-05-02 US disclosed
EP-0534436-A1 Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel Shin-Etsu Chemical Co., Ltd. (JP) 1993-03-31 EP disclosed
US-5091558-A Topical administeration SYNTEX (U.S.A.) INC. (US) 1992-02-25 US disclosed
EP-0150831-B1 NAPHTHALENE ANTI-PSORIATIC AGENTS SYNTEX (U.S.A.) INC. (US) 1988-08-10 EP disclosed
EP-0150831-A2 Naphthalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1985-08-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613509-B2 Radical polymerization control agent and radical polymerization control method PPOX, NOX4, CROCC MAOA 204/4885MAOB 358/4885ELANE 4115/4885
US-20210122692-A1 RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD PPOX, NOX4, CROCC MAOA 204/4885MAOB 358/4885ELANE 4115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.