Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.68 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9729584 | 0.88 | MTNR1A (0.73) | MTNR1AALOX5MAPTMEN1HSP90AA1 | |
| Formamide SCHEMBL9729804 | 0.87 | MTNR1A (0.56) | MTNR1AALOX5MAPTMEN1HSP90AA1 | |
| Formamide SCHEMBL9729455 | 0.84 | ALOX5 (0.60) | MTNR1AALOX5ALOX12PTGS1PTGS2 | |
| Formamide SCHEMBL9730206 | 0.82 | ALOX5 (0.61) | MTNR1AALOX5ALOX12PTGS1PTGS2 | |
| Formamide SCHEMBL9729746 | 0.82 | ALOX5 (0.63) | MTNR1AALOX5ALOX12PTGS1PTGS2 | |
| Formamide SCHEMBL9729689 | 0.82 | ALOX5 (0.63) | MTNR1AALOX5ALOX12PTGS1PTGS2 | |
| Formamide SCHEMBL9729701 | 0.81 | ALOX5 (0.62) | MTNR1AALOX5MAOBALOX12PTGS1 | |
| SCHEMBL7201065 | 0.81 | MTNR1A (1.00) | MTNR1AALOX5MAPTMEN1HSP90AA1 | |
| Formamide SCHEMBL9729960 | 0.80 | ALOX5 (0.56) | MTNR1AALOX5MAPTMAOBALOX12 | |
| Formamide SCHEMBL9729662 | 0.79 | ALOX5 (0.64) | MTNR1AALOX5MAOBALOX12PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |