Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.40 |
| ▸ | RELA | Q04206 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL9730233 | 0.87 | MTNR1A (0.68) | MTNR1AALOX5NR1H4MAPTGAA | |
| Hydrochloric Acid SCHEMBL9729584 | 0.81 | MTNR1A (0.73) | MTNR1AALOX5NR1H4MAPTGAA | |
| Formamide SCHEMBL9729455 | 0.78 | ALOX5 (0.60) | MTNR1AALOX5PTGS1PTGS2ALOX12 | |
| Formamide SCHEMBL9730206 | 0.76 | ALOX5 (0.61) | MTNR1AALOX5PTGS1PTGS2ALOX12 | |
| Formamide SCHEMBL9729689 | 0.76 | ALOX5 (0.63) | MTNR1AALOX5PTGS1PTGS2ALOX12 | |
| Formamide SCHEMBL9729746 | 0.76 | ALOX5 (0.63) | MTNR1AALOX5PTGS1PTGS2ALOX12 | |
| Formamide SCHEMBL9729701 | 0.75 | ALOX5 (0.62) | MTNR1AALOX5CA12CA9PTGS1 | |
| Formamide SCHEMBL9729960 | 0.75 | ALOX5 (0.56) | MTNR1AALOX5MAPTPTGS1PTGS2 | |
| SCHEMBL9729800 | 0.75 | ALOX5 (0.83) | MTNR1AALOX5PTGS1PTGS2ALOX12 | |
| SCHEMBL9729530 | 0.73 | ALOX5 (0.54) | MTNR1AALOX5NR1H4CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |