Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10639923 | 0.79 | LMNA (0.48) | MAPTALDH1A1TSHRHTTTP53 | |
| SCHEMBL10639930 | 0.79 | LMNA (0.48) | MAPTALDH1A1TSHRHTTTP53 | |
| SCHEMBL5144238 | 0.76 | LMNA (0.44) | ALDH1A1KMT2ALMNASMN1; SMN2ACHE | |
| SCHEMBL5144242 | 0.76 | LMNA (0.44) | ALDH1A1KMT2ALMNASMN1; SMN2ACHE | |
| SCHEMBL9730370 | 0.75 | LMNA (0.54) | MAPTKDM4EALDH1A1TSHRMEN1 | |
| SCHEMBL10641110 | 0.72 | TNF (0.49) | MAPTALDH1A1TSHRHTTTP53 | |
| SCHEMBL10641107 | 0.72 | TNF (0.49) | MAPTALDH1A1TSHRHTTTP53 | |
| SCHEMBL9729392 | 0.72 | HSD17B10 (0.46) | MAPTKDM4EHPGDALDH1A1TSHR | |
| SCHEMBL10636977 | 0.70 | LMNA (0.46) | MAPTALDH1A1TSHRHTTTP53 | |
| SCHEMBL10639415 | 0.70 | KDM4E (0.46) | MAPTKDM4EHPGDALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106863-A | Antiulcer agents, gastrointestinal disorders | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |