Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP3 | P08254 | 3/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10637009 | 0.82 | LMNA (0.43) | FFAR4FFAR1SPHK1LMNAGPR84 | |
| SCHEMBL7438751 | 0.75 | CES2 (0.41) | FFAR4FFAR1LMNAGPR84MEN1 | |
| SCHEMBL7440935 | 0.73 | CES2 (0.39) | FFAR4FFAR1LMNAGPR84MEN1 | |
| SCHEMBL5014639 | 0.72 | CA2 (0.42) | FFAR4FFAR1SPHK1LMNAMEN1 | |
| SCHEMBL15209687 | 0.72 | CA2 (0.42) | FFAR4FFAR1SPHK1LMNAMEN1 | |
| SCHEMBL8195637 | 0.72 | CA2 (0.42) | FFAR4FFAR1SPHK1LMNAMEN1 | |
| SCHEMBL18301373 | 0.71 | LMNA (0.43) | FFAR1SPHK1LMNAHSPD1BLM | |
| SCHEMBL11067651 | 0.71 | LMNA (0.43) | FFAR1SPHK1LMNAHSPD1BLM | |
| SCHEMBL23498813 | 0.71 | CA2 (0.48) | FFAR4FFAR1LMNAGPR84MEN1 | |
| SCHEMBL16702733 | 0.71 | CA2 (0.48) | FFAR4FFAR1LMNAGPR84MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |