Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730321 | 0.77 | METAP1 (0.50) | CYP3A4ALDH1A1CA1CA2CA4 | |
| SCHEMBL2871970 | 0.77 | — | — | |
| SCHEMBL7981630 | 0.74 | MAPT (0.75) | MAPTCYP3A4ALDH1A1KDM4EMAOA | |
| SCHEMBL25493088 | 0.71 | HTR2A (0.41) | LMNA | |
| SCHEMBL9731711 | 0.71 | ACHE (0.42) | MAPTCYP3A4ALDH1A1ACHECA1 | |
| SCHEMBL6933142 | 0.70 | AKR1C3 (0.37) | MAPTHPGDMEN1KMT2ALMNA | |
| SCHEMBL16156009 | 0.67 | CYP3A4 (0.56) | MAPTCYP3A4ALDH1A1KDM4EHPGD | |
| SCHEMBL31369146 | 0.67 | CYP3A4 (0.62) | MAPTCYP3A4MAOAACHECA1 | |
| SCHEMBL8938848 | 0.67 | LMNA (0.50) | MAPTCYP3A4ALDH1A1KDM4EHPGD | |
| SCHEMBL28642174 | 0.67 | CYP3A4 (0.56) | MAPTCYP3A4ALDH1A1KDM4EMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126461-A | Silica in organic solution | SHELL RESEARCH LIMITED (GB) | 1992-06-30 | — | — | US | disclosed |