Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973103 | 0.86 | LMNA (0.62) | LMNAPOLBSTING1GAAKDM4E | |
| SCHEMBL12921935 | 0.84 | ATM (0.69) | LMNAPOLBATMNPC1RAB9A | |
| SCHEMBL973052 | 0.84 | ATM (0.69) | LMNAPOLBATMSTING1GAA | |
| SCHEMBL1136137 | 0.84 | LMNA (0.54) | LMNAPOLBSTING1GAAKDM4E | |
| SCHEMBL17144786 | 0.83 | LMNA (0.53) | LMNAPOLBNPC1RAB9ASTING1 | |
| SCHEMBL971255 | 0.82 | ATM (0.50) | LMNAPOLBATMNPC1RAB9A | |
| SCHEMBL13491717 | 0.82 | LMNA (0.52) | LMNAPOLBGAAKDM4EMAPT | |
| SCHEMBL1135680 | 0.82 | LMNA (0.54) | LMNAPOLBSTING1GAAKDM4E | |
| SCHEMBL15063349 | 0.81 | LMNA (0.51) | LMNAPOLBSTING1GAAKDM4E | |
| SCHEMBL1136025 | 0.81 | LMNA (0.51) | LMNAPOLBSTING1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580971-B2 | Alkyl-analide producing method | BAYER CROPSCIENCE AG (DE) | 2013-11-12 | — | — | US | disclosed |
| US-8580971-B2 | Alkyl-analide producing method | BAYER CROPSCIENCE AG (DE) | 2013-11-12 | — | — | US | disclosed |
| US-8580971-B2 | Alkyl-analide producing method | BAYER CROPSCIENCE AG (DE) | 2013-11-12 | — | — | US | disclosed |
| EP-2257530-B1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2011-10-12 | — | — | EP | disclosed |
| EP-2257530-B1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2011-10-12 | — | — | EP | disclosed |
| CN-101133032-B | Pyrazolylcarboxanilides | BAYER CROPSCIENCE AG | 2011-06-08 | — | — | CN | disclosed |
| US-20110003999-A1 | Process for Preparing Substituted Biphenylanilides | BAYER CROPSCIENCE AG (DE) | 2011-01-06 | — | — | US | disclosed |
| US-20110003999-A1 | Process for Preparing Substituted Biphenylanilides | BAYER CROPSCIENCE AG (DE) | 2011-01-06 | — | — | US | disclosed |
| EP-1490342-B1 | DISUBSTITUTED PYRAZOLYL CARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-12-15 | — | — | EP | disclosed |
| EP-1490342-B1 | DISUBSTITUTED PYRAZOLYL CARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-12-15 | — | — | EP | disclosed |
| EP-1856054-B1 | PYRAZOLYLCARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2008-09-17 | — | — | EP | disclosed |
| CN-101133032-A | Pyrazolylcarboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-02-27 | — | — | CN | disclosed |
| US-7329633-B2 | Disubstituted pyrazolylcarboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-02-12 | — | — | US | disclosed |
| US-7329633-B2 | Disubstituted pyrazolylcarboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-02-12 | — | — | US | disclosed |
| US-7329633-B2 | Disubstituted pyrazolylcarboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-02-12 | — | — | US | disclosed |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-01-17 | — | — | US | disclosed |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-01-17 | — | — | US | disclosed |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-01-17 | — | — | US | disclosed |
| US-20060116414-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-06-01 | — | — | US | disclosed |
| CN-1646494-A | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2005-07-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116414-A1 | Disubstituted pyrazolyl carboxanilides | MRPL21, RRS1, CBR3 | LMNA 4412/4885POLB 1290/4885ATM 1894/4885 |
| US-20110003999-A1 | Process for Preparing Substituted Biphenylanilides | DDT, PAH, THOP1 | LMNA 3959/4885POLB 425/4885ATM 3682/4885 |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | MRPL21, CBR3, CBR1 | LMNA 4600/4885POLB 1757/4885ATM 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.