Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.77 |
| ▸ | RAB9A | P51151 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | PKM | P14618 | 1/20 | 0.77 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640087 | 0.91 | SMN1; SMN2 (0.68) | NPC1RAB9ASMN1; SMN2PKMEPHX2 | |
| SCHEMBL23119199 | 0.87 | NPC1 (0.75) | NPC1RAB9ASMN1; SMN2PKMEPHX2 | |
| SCHEMBL8641864 | 0.87 | SMN1; SMN2 (0.63) | NPC1RAB9ASMN1; SMN2PKMEPHX2 | |
| SCHEMBL22447941 | 0.87 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2PKMEPHX2 | |
| SCHEMBL9486768 | 0.86 | MEN1 (0.62) | NPC1RAB9ASMN1; SMN2PKMEPHX2 | |
| SCHEMBL17842262 | 0.84 | RAB9A (0.75) | NPC1RAB9ASMN1; SMN2PKMEPHX2 | |
| SCHEMBL8959041 | 0.84 | PKM (0.56) | NPC1RAB9ASMN1; SMN2PKMEPHX2 | |
| SCHEMBL8959189 | 0.84 | PKM (0.56) | NPC1RAB9ASMN1; SMN2PKMEPHX2 | |
| SCHEMBL8638423 | 0.84 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2PKMEPHX2 | |
| SCHEMBL23975373 | 0.84 | SMN1; SMN2 (0.89) | NPC1RAB9ASMN1; SMN2PKMEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132326-A | Insecticides which interfere with hormonal activity | BASF AKTIENGESELLSCHAFT (DE) | 1992-07-21 | — | — | US | disclosed |