Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732039 | 0.93 | ESR2 (0.31) | ESR2 | |
| SCHEMBL9582023 | 0.92 | GABRA2 (0.36) | GAASMN1; SMN2TDP1 | |
| SCHEMBL9730517 | 0.92 | DDR1 (0.31) | ESR2 | |
| SCHEMBL9730727 | 0.91 | KDM5B (0.35) | ESR2ELANEGAAKDM5B | |
| SCHEMBL9730772 | 0.84 | HCAR1 (0.38) | ELANE | |
| SCHEMBL9581479 | 0.84 | ESR2 (0.32) | ESR2ELANEGAAKDM5B | |
| SCHEMBL9582173 | 0.82 | DDR1 (0.32) | ESR2KDM5B | |
| SCHEMBL9582286 | 0.82 | GABRA2 (0.38) | GAASMN1; SMN2TDP1 | |
| SCHEMBL9339490 | 0.80 | GABRA2 (0.38) | — | |
| SCHEMBL9581956 | 0.79 | TDP1 (0.38) | GAASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5109004-A | Cyano phenyl-substituted with heterocylic compound; insecticides, miticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-28 | — | — | US | disclosed |
| EP-0398499-A2 | Insecticides | ZENECA LIMITED (GB) | 1990-11-22 | — | — | EP | disclosed |