Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LCAT | P04180 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730727 | 0.83 | KDM5B (0.35) | GAAALDH1A1KDM4EESR2KDM5B | |
| SCHEMBL9765875 | 0.80 | ALDH1A1 (0.36) | GAASMN1; SMN2TDP1ALDH1A1KDM4E | |
| SCHEMBL9765814 | 0.80 | ALDH1A1 (0.49) | GAASMN1; SMN2TDP1ALDH1A1MAPT | |
| SCHEMBL9581996 | 0.80 | HCAR1 (0.40) | ESR2 | |
| SCHEMBL9581479 | 0.79 | ESR2 (0.32) | GAAESR2CYP11B1CYP11B2KDM5B | |
| SCHEMBL9582286 | 0.78 | GABRA2 (0.38) | GAASMN1; SMN2TDP1ALDH1A1KDM4E | |
| SCHEMBL9582173 | 0.78 | DDR1 (0.32) | ESR2KDM5BALPLALPI | |
| SCHEMBL9765906 | 0.76 | ALDH1A1 (0.39) | GAASMN1; SMN2TDP1ALDH1A1KDM4E | |
| SCHEMBL9730834 | 0.74 | ESR2 (0.33) | GAASMN1; SMN2TDP1ESR2KDM5B | |
| SCHEMBL9581956 | 0.74 | TDP1 (0.38) | GAASMN1; SMN2TDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990512-A | Insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-05 | — | — | US | disclosed |
| EP-0357201-A2 | Pyridyl pyrimidinone derivatives with an insecticidal activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-03-07 | — | — | EP | disclosed |