SCHEMBL9730741

SCHEMBL9730741

CN(C)C(=O)NOc1cc(Cl)cc(Cl)c1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
APEX1 P27695 1/20 0.39
MAPT P10636 2/20 0.38
CARM1 Q86X55 1/20 0.38
PRMT6 Q96LA8 1/20 0.38
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 1/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
PKM P14618 1/20 0.34
RAB9A P51151 1/20 0.34
OGG1 O15527 1/20 0.34
TPMT P51580 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trichloroacetic Acid SCHEMBL9731226 0.91 TSHR (0.36) TSHRAPEX1MAPTCARM1PRMT6
SCHEMBL9674646 0.83 CARM1 (0.40) MAPTCARM1PRMT6ALDH1A1KDM4E
SCHEMBL10524163 0.79 LMNA (0.44) ALDH1A1KDM4EGAAPKMRAB9A
Trichloroacetic Acid SCHEMBL9732406 0.76 CARM1 (0.36) MAPTCARM1PRMT6ALDH1A1GAA
SCHEMBL9731148 0.73 APEX1 (0.45) TSHRAPEX1ALDH1A1KDM4EHPGD
SCHEMBL7276010 0.71 TSHR (0.66) TSHRAPEX1MAPTALDH1A1GAA
SCHEMBL7846468 0.71 MAPT (0.38) TSHRMAPTCARM1PRMT6ALDH1A1
SCHEMBL11003719 0.70 ALDH1A1 (0.39) MAPTCARM1PRMT6ALDH1A1KDM4E
SCHEMBL10579775 0.70 MAPT (0.58) MAPTALDH1A1KDM4EGLAGAA
SCHEMBL9674597 0.69 MAPT (0.57) TSHRMAPTALDH1A1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5112385-A Useful in rice paddies KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1992-05-12 US disclosed
US-4968341-A PRE-AND POSTEMERGENCE HERBICIDES KUMIAI CHEMICAL INDUSTRY CO. (JP) 1990-11-06 US disclosed
EP-0183174-B1 SUBSTITUTED PHENOXY UREA, PROCESSES FOR ITS PREPARATION AND HERBICIDE CONTAINING IT AS ACTIVE INGREDIENT KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-10-26 EP disclosed
EP-0183174-A2 Substituted phenoxy urea, processes for its preparation and herbicide containing it as active ingredient KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1986-06-04 EP disclosed