Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 3/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | KDM4B | O94953 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18864231 | 0.90 | MAPT (0.46) | ALDH1A1MAPTL3MBTL1KDM5CKDM5B | |
| SCHEMBL18864232 | 0.88 | FTO (0.53) | ALDH1A1MAPTL3MBTL1KDM5CKDM5B | |
| SCHEMBL3807628 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTL3MBTL1KDM5CKDM5B | |
| SCHEMBL9731392 | 0.81 | SMN1; SMN2 (0.42) | ALDH1A1MAPTL3MBTL1KDM5CKDM5B | |
| SCHEMBL5251044 | 0.77 | PARP1 (0.49) | ALDH1A1MAPTMLYCDKDM4ENAMPT | |
| SCHEMBL8842629 | 0.77 | LOXL2 (0.50) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL30260189 | 0.77 | AURKA (0.49) | KDM5CKDM5BKDM5AKDM4CKDM5D | |
| SCHEMBL29066364 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1KDM5CKDM5B | |
| SCHEMBL9731029 | 0.76 | SCN9A (0.41) | ALDH1A1MAPTL3MBTL1SCN9AMLYCD | |
| SCHEMBL16569986 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1KDM5CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130317-A | Immunosuppressants and fibrosuppressants for metabolism of collagen | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |