Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 7/20 | 0.53 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 4/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.53 |
| ▸ | KDM5A | P29375 | 4/20 | 0.53 |
| ▸ | KDM5C | P41229 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | KDM6B | O15054 | 2/20 | 0.53 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.53 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4A | O75164 | 2/20 | 0.53 |
| ▸ | TET3 | O43151 | 1/20 | 0.53 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.53 |
| ▸ | ASPH | Q12797 | 1/20 | 0.53 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.53 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.53 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.53 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18864231 | 0.92 | MAPT (0.46) | FTOKDM5BALKBH5KDM4CKDM5A | |
| SCHEMBL9730848 | 0.88 | ALDH1A1 (0.43) | FTOKDM5BALKBH5KDM4CKDM5A | |
| SCHEMBL3854386 | 0.84 | KDM5B (0.57) | FTOKDM5BALKBH5KDM4CKDM5A | |
| SCHEMBL5808530 | 0.81 | ALDH1A1 (0.65) | FTOKDM5BALKBH5KDM4CKDM5A | |
| SCHEMBL6990109 | 0.80 | LPAR1 (0.53) | FTOKDM5BALKBH5KDM4CKDM5A | |
| SCHEMBL9731016 | 0.78 | HCAR2 (0.40) | KDM4EALDH1A1MLYCDSCN9A | |
| SCHEMBL6993029 | 0.78 | ALDH1A1 (0.48) | FTOKDM5BALKBH5KDM4CKDM5A | |
| SCHEMBL6239722 | 0.77 | KDM5B (0.49) | FTOKDM5BALKBH5KDM4CKDM5A | |
| SCHEMBL6985928 | 0.77 | KDM5B (0.49) | FTOKDM5BALKBH5KDM4CKDM5A | |
| SCHEMBL9731029 | 0.77 | SCN9A (0.41) | KDM4EALDH1A1MAPTL3MBTL1MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240307477-A1 | COMPOSITION FOR PREVENTING OR TREATING LIVER FIBROSIS INCLUDING SANGUISORBA OFFICINALIS EXTRACT AS ACTIVE INGREDIENT | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2024-09-19 | — | — | US | disclosed |
| WO-2023063663-A1 | COMPOSITION FOR PREVENTING OR TREATING HEPATIC FIBROSIS, COMPRISING BETA-GUANIDINOPROPIONIC ACID | 주식회사 휴엔켐 | 2023-04-20 | — | — | WO | disclosed |
| US-9895370-B2 | Pharmaceutical composition for preventing or treating of cirrhosis of liver comprising G protein coupled receptor 119 ligand as an active ingredient | PHARMEDIX.CO., LTD (KR) | 2018-02-20 | — | — | US | disclosed |
| US-20170143714-A1 | Pharmaceutical composition for preventing or treating of cirrhosis of liver comprising G protein coupled receptor 119 ligand as an active ingredient | DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2017-05-25 | — | — | US | disclosed |