Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439448 | 0.89 | NR4A2 (0.59) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL442246 | 0.85 | KDM4E (0.47) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL9730943 | 0.83 | MAPT (0.47) | NR4A2KDM4ETDP1MAPTL3MBTL1 | |
| SCHEMBL441437 | 0.80 | MAPT (0.57) | NR4A2CYP3A4MAPTALDH1A1RAB9A | |
| SCHEMBL11637772 | 0.79 | KDM4E (0.50) | NR4A2KDM4ETDP1MAPTL3MBTL1 | |
| SCHEMBL439849 | 0.78 | POLB (0.43) | KDM4ECYP3A4MAPTHTTLMNA | |
| SCHEMBL11546436 | 0.76 | KDM4E (0.50) | NR4A2KDM4ETDP1NCF1MAPT | |
| SCHEMBL11543194 | 0.75 | NR4A2 (0.51) | NR4A2KDM4ETDP1MAPTL3MBTL1 | |
| SCHEMBL438207 | 0.73 | MAPT (0.53) | NR4A2CYP3A4MAPTALDH1A1RAB9A | |
| SCHEMBL439579 | 0.71 | NR4A2 (0.65) | NR4A2KDM4ETDP1NCF1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |