Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGFBP3 | P17936 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732349 | 0.89 | LMNA (0.34) | IGFBP3MEN1LMNAKMT2ACNR2 | |
| SCHEMBL9730941 | 0.74 | MAPT (0.40) | MEN1LMNAPOLBKMT2A | |
| SCHEMBL274802 | 0.73 | IGFBP3 (0.43) | IGFBP3MEN1LMNAPOLBKMT2A | |
| SCHEMBL9731303 | 0.72 | PARP1 (0.39) | MEN1LMNAPOLBKMT2A | |
| SCHEMBL9732757 | 0.72 | KDM4E (0.35) | MEN1LMNAKMT2A | |
| SCHEMBL9731597 | 0.71 | KDM4E (0.33) | MEN1LMNAKMT2ACNR2 | |
| SCHEMBL9732583 | 0.71 | ERN1 (0.33) | MEN1LMNAPOLBKMT2A | |
| SCHEMBL9731095 | 0.70 | MAPT (0.35) | — | |
| SCHEMBL9731359 | 0.70 | MAPT (0.35) | — | |
| SCHEMBL9730980 | 0.69 | EGFR (0.48) | MEN1LMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |