Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731516 | 0.82 | EGFR (0.44) | EGFRKDM4ENPC1RAB9AMAPT | |
| SCHEMBL29953541 | 0.79 | ACHE (0.41) | ECE2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL9732930 | 0.78 | CD74 (0.60) | ECE2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL9732747 | 0.76 | RAB9A (0.59) | ECE2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL9731621 | 0.75 | IDO1 (0.46) | EGFRKDM4ENPC1RAB9AMAPT | |
| SCHEMBL9731523 | 0.74 | EGFR (0.42) | EGFRKDM4ENPC1RAB9AMAPT | |
| SCHEMBL9731192 | 0.73 | EGFR (0.42) | EGFRKDM4ERAB9AMAPTL3MBTL1 | |
| SCHEMBL9731167 | 0.73 | KDM4E (0.51) | EGFRECE2KDM4ENPC1RAB9A | |
| Formamide SCHEMBL9730999 | 0.73 | CYP1A2 (0.37) | ECE2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL9731151 | 0.72 | EGFR (0.46) | EGFRKDM4ENPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |