Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 4/20 | 0.40 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL9730999 | 0.82 | CYP1A2 (0.37) | ACHEERN1ECE2CYP1A2KDM4E | |
| SCHEMBL9730993 | 0.79 | EGFR (0.41) | ACHEECE2CYP1A2KDM4ELMNA | |
| SCHEMBL9071311 | 0.78 | ERN1 (0.47) | ERN1HTR2BCYP1A2KDM4EALDH1A1 | |
| SCHEMBL29952948 | 0.78 | MAPT (0.47) | CCR1ERN1CYP1A2KDM4EALDH1A1 | |
| SCHEMBL2170729 | 0.78 | RAB9A (0.44) | CCR1ERN1KDM4ELMNAALDH1A1 | |
| SCHEMBL29951387 | 0.78 | ERN1 (0.47) | ERN1HTR2BCYP1A2KDM4EALDH1A1 | |
| SCHEMBL4615123 | 0.74 | ACHE (0.48) | ACHECYP1A2KDM4ELMNAALDH1A1 | |
| SCHEMBL28449950 | 0.74 | PDE10A (0.51) | ERN1KDM4ELMNAALDH1A1MAPT | |
| SCHEMBL4818968 | 0.73 | ALDH1A1 (0.62) | ERN1ALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL29694379 | 0.72 | KDM4E (0.64) | CCR1CYP1A2KDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |