Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730827 | 0.82 | POLB (0.45) | EGFRKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL29950812 | 0.79 | ERN1 (0.42) | KDM4EALDH1A1MAPTPOLBGAA | |
| SCHEMBL9731570 | 0.78 | KDM4E (0.43) | EGFRKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL9731149 | 0.76 | MAPT (0.46) | EGFRKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL9731764 | 0.74 | MAPT (0.47) | EGFRKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL9730993 | 0.73 | EGFR (0.41) | EGFRKDM4EALDH1A1MAPTPOLB | |
| Formamide SCHEMBL9731196 | 0.73 | ESR2 (0.34) | ERN1 | |
| SCHEMBL9732630 | 0.71 | MAPT (0.55) | EGFRKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL9731190 | 0.71 | NQO2 (0.32) | KDM4EALDH1A1MAPTPOLBGAA | |
| SCHEMBL9732410 | 0.70 | EGFR (0.56) | EGFRKDM4EALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |