Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731132 | 0.82 | KCNN4 (0.47) | GAASMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL7426505 | 0.79 | CYP1A2 (0.59) | GAASMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL14428964 | 0.78 | CYP3A4 (0.50) | CYP2E1CYP3A4CYP2A6HCAR1L3MBTL1 | |
| SCHEMBL8502061 | 0.78 | CYP3A4 (0.47) | SMN1; SMN2CYP2E1CYP3A4CYP2A6ALDH1A1 | |
| SCHEMBL15218939 | 0.78 | NR4A1 (0.54) | GAASMN1; SMN2CYP2E1CYP3A4CYP2A6 | |
| SCHEMBL175160 | 0.78 | ICMT (0.37) | SMN1; SMN2MEN1KMT2ACYP2E1CYP3A4 | |
| SCHEMBL14237644 | 0.77 | MAOA (0.41) | GAAMEN1KMT2ACYP3A4LMNA | |
| SCHEMBL15921015 | 0.75 | SMN1; SMN2 (0.42) | GAASMN1; SMN2MEN1KMT2AHCAR1 | |
| SCHEMBL15921161 | 0.75 | SMN1; SMN2 (0.42) | GAASMN1; SMN2MEN1KMT2AHCAR1 | |
| SCHEMBL19029697 | 0.75 | CYP3A4 (0.47) | CYP2E1CYP3A4CYP2A6HCAR1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4602031-A | Anti-depressant imidazoles, compositions and use | EISAI CO., LTD. (JP) | 1986-07-22 | — | — | US | disclosed |
| US-4533669-A | NONTOXIC | EISAI CO., LTD. (JP) | 1985-08-06 | — | — | US | disclosed |
| US-4402966-A | Acylaminophenyl imidazoles and anti-depressing agent containing the same | EISAI CO., LTD. (JP) | 1983-09-06 | — | — | US | disclosed |
| US-4301169-A | Novel imidazole compound and anti-depressing agent containing the same | EISAI CO., LTD. (JP) | 1981-11-17 | — | — | US | disclosed |