Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL9731196 | 0.82 | ESR2 (0.34) | ERN1 | |
| SCHEMBL9731192 | 0.79 | EGFR (0.42) | ERN1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL16431491 | 0.78 | ERN1 (0.47) | ERN1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL30081467 | 0.78 | ALDH1A1 (0.51) | ERN1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL12152493 | 0.78 | P2RX7 (0.41) | ERN1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL29950678 | 0.78 | ERN1 (0.47) | ERN1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL4615123 | 0.74 | ACHE (0.48) | KMT2AKDM4EIDO1RAB9ANPSR1 | |
| SCHEMBL11276512 | 0.74 | ALDH1A1 (0.44) | ERN1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL9731190 | 0.73 | NQO2 (0.32) | ERN1MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL31466752 | 0.72 | NR4A1 (0.52) | MEN1KMT2AKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |