Tyrosine

Tyrosine

SCHEMBL9732180

NC(Cc1ccc(O)cc1)C(=O)O.Nc1ncnc2[nH]cnc12

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.57
PTGS1 P23219 2/20 0.42
ALPI P09923 1/20 0.42
PKM P14618 1/20 0.42
XIAP P98170 1/20 0.42
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
EGFR P00533 1/20 0.41
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
ALOX15 P16050 1/20 0.41
HTR2A P28223 1/20 0.41
PTGS2 P35354 1/20 0.41
RECQL P46063 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
YARS1 P54577 2/20 0.39
ERAP2 Q6P179 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL9732191 0.82 SLC7A5 (0.56) SLC7A5PTGS1ALPIPKMXIAP
Histidine SCHEMBL7197901 0.79 CYP3A4 (0.37) SLC7A5KDM4EHIF1A
Adenine SCHEMBL1577865 0.78 SLC7A5 (0.47) SLC7A5CIT
Adenine SCHEMBL4201611 0.77 PTGS1 (0.41) SLC7A5PTGS1
Adenine SCHEMBL14125907 0.76 PI4KA (0.39) EGFR
Tyrosine SCHEMBL1580 0.76 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL1581 0.76 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL11676367 0.76 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL10978820 0.76 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL11676395 0.76 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1080306-C Adjusting and controlling factor for expression of nitrile solution deenzyme and gene thereof MITSUBISHI RAYON CO (JP) 2002-03-06 CN disclosed
EP-0332216-B1 NOVEL SUBSTANCE FOR AGRICULTURAL USE AND PROCESS FOR ITS PRODUCTION Kaken Pharmaceutical Co., Ltd. (JP) 1992-11-25 EP disclosed
US-5102794-A Culturing and isolating microorganism KITASATOSPORIA KAKEN PHARMACEUTICAL CO., LTD. (JP) 1992-04-07 US disclosed
US-5032611-A Rice plant disease prevention KAKEN PHARMACEUTICAL CO., LTD. (JP) 1991-07-16 US disclosed
EP-0332216-A1 Novel substance for agricultural use and process for its production Kaken Pharmaceutical Co., Ltd. (JP) 1989-09-13 EP disclosed
US-4784953-A NOCARDIA WHICH FORMS 4(3-PROPIONIC ACID-5-HYDROXY-7-METHYL INDANONE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1988-11-15 US disclosed