Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SARS1 | P49591 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.33 |
| ▸ | NNMT | P40261 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 2/20 | 0.32 |
| ▸ | PCMT1 | P22061 | 2/20 | 0.32 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.32 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.32 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | RNMT | O43148 | 1/20 | 0.32 |
| ▸ | INMT | O95050 | 1/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mercaptopurine Anhydrous SCHEMBL6897146 | 0.83 | PTGS1 (0.44) | PTGS1SLC7A11CYP3A4SLC7A5 | |
| Adenine SCHEMBL4201626 | 0.81 | PI4KA (0.55) | PTGS1SLC7A11ALDH1A1CYP3A4 | |
| Adenine SCHEMBL1577865 | 0.81 | SLC7A5 (0.47) | ALDH1A1CYP3A4SLC7A5EHMT2NSD2 | |
| Adenine SCHEMBL9663399 | 0.78 | MARS1 (0.43) | EHMT2NNMTNSD2DOT1LSETD7 | |
| Adenine SCHEMBL385841 | 0.77 | PI4KA (0.45) | — | |
| Adenine SCHEMBL23928076 | 0.77 | MARS1 (0.42) | ALDH1A1EHMT2NNMTNSD2DOT1L | |
| Histidine SCHEMBL7197901 | 0.77 | CYP3A4 (0.37) | ALDH1A1CYP3A4SLC7A5EHMT2NNMT | |
| Tyrosine SCHEMBL9732180 | 0.77 | SLC7A5 (0.57) | PTGS1SLC7A5 | |
| Adenine SCHEMBL14125907 | 0.76 | PI4KA (0.39) | ALDH1A1 | |
| Adenine SCHEMBL28763031 | 0.76 | PI4KA (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8206931-B2 | Methods of identifying modulators of cellular glycosylation using GTRAP3-18 | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-06-26 | — | — | US | disclosed |
| EP-1595129-A4 | METHODS OF IDENTIFYING MODULATORS OF CELLULAR GLYCOSYLATION USING GTRAP3-18 | UNIV JOHNS HOPKINS (US) | 2009-03-04 | — | — | EP | disclosed |
| US-20060211042-A1 | Methods of identifying modulators of cellular glycosylation using gtrap3-18 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-09-21 | — | — | US | disclosed |
| EP-1595129-A2 | METHODS OF IDENTIFYING MODULATORS OF CELLULAR GLYCOSYLATION USING GTRAP3-18 | THE JOHNS HOPKINS UNIVERSITY (US) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004065932-A2 | METHODS OF IDENTIFYING MODULATORS OF CELLULAR GLYCOSYLATION USING GTRAP3-18 | THE JOHNS HOPKINS UNIVERSITY (US) | 2004-08-05 | — | — | WO | disclosed |