Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL971170 | 1.00 | ESR1 (0.33) | ESR1ESR2ALDH1A1L3MBTL1 | |
| SCHEMBL972366 | 0.98 | ESR1 (0.31) | ESR1ESR2ALDH1A1L3MBTL1 | |
| SCHEMBL3741763 | 0.91 | PGR (0.38) | — | |
| SCHEMBL3735874 | 0.89 | PGR (0.37) | — | |
| SCHEMBL17685432 | 0.73 | — | — | |
| SCHEMBL17685444 | 0.72 | — | — | |
| SCHEMBL17685451 | 0.72 | — | — | |
| SCHEMBL17685445 | 0.72 | — | — | |
| SCHEMBL7700923 | 0.71 | PGR (0.46) | — | |
| SCHEMBL2409843 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274289-B1 | ELECTROLUMINESCENT MATERIALS | LOMOX LTD (GB) | 2016-04-20 | — | — | EP | disclosed |
| US-20160056389-A1 | Electroluminescent Materials Comprising Fluorene Derivatives | LOMOX LTD (GB) | 2016-02-25 | — | — | US | disclosed |
| US-9029537-B2 | Electroluminescent materials | LOMOX LIMITED (GB) | 2015-05-12 | — | — | US | disclosed |
| EP-2483368-B1 | ELECTROLUMINESCENT MATERIALS COMPRISING FLUORENE DERIVATIVES | LOMOX LTD (GB) | 2014-12-24 | — | — | EP | disclosed |
| US-20130317233-A1 | Electroluminescent Materials | LOMOX LIMITED (GB) | 2013-11-28 | — | — | US | disclosed |
| US-20130037752-A1 | ELECTROLUMINESCENT MATERIALS COMPRISING FLUORENE DERIVATIVES | LOMOX LIMITED (GB) | 2013-02-14 | — | — | US | disclosed |
| US-20110015404-A1 | Electroluminescent Materials | LOMOX LIMITED (GB) | 2011-01-20 | — | — | US | disclosed |
| EP-2274289-A1 | ELECTROLUMINESCENT MATERIALS | Lomox Limited (GB) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009087364-A1 | ELECTROLUMINESCENT MATERIALS | LOMOX LIMITED (GB) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130037752-A1 | ELECTROLUMINESCENT MATERIALS COMPRISING FLUORENE DERIVATIVES | SPIN2B, FLNB, LMNB2 | ESR1 742/4885ESR2 169/4885ALDH1A1 1769/4885 |
| US-20160056389-A1 | Electroluminescent Materials Comprising Fluorene Derivatives | FLNB, LMNB2, SPIN2B | ESR1 793/4885ESR2 205/4885ALDH1A1 1665/4885 |
| US-20110015404-A1 | Electroluminescent Materials | ZYX, FLNB, LMNB2 | ESR1 452/4885ESR2 471/4885ALDH1A1 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.