Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 5/20 | 0.59 |
| ▸ | ICMT | O60725 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023153 | 0.89 | LTB4R (0.63) | LTB4RALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL9584018 | 0.88 | PLA2G2A (0.61) | ALDH1A1LMNAPLA2G2A | |
| SCHEMBL9023552 | 0.84 | LTB4R (0.74) | LTB4RALDH1A1SMN1; SMN2LMNALTB4R2 | |
| SCHEMBL21178247 | 0.83 | LTB4R (0.68) | LTB4RLTB4R2KMT2AMEN1POLB | |
| SCHEMBL28524187 | 0.83 | LTB4R (0.57) | LTB4RALDH1A1LMNAPLA2G2APOLB | |
| SCHEMBL28910240 | 0.81 | LTB4R (0.56) | LTB4RALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL9732535 | 0.79 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2LMNAHTTTDP1 | |
| SCHEMBL17829696 | 0.79 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2LMNAHTTTDP1 | |
| SCHEMBL28530566 | 0.78 | LTB4R (0.52) | LTB4RALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL6642863 | 0.78 | LTB4R (0.59) | LTB4RALDH1A1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007829-A1 | INDOLE-3-METHANAMINES USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |