SCHEMBL973305

SCHEMBL973305

Cc1ccc(Oc2ccc(S(N)(=O)=O)cc2)nc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
HTT P42858 1/20 0.55
CA1 P00915 6/20 0.52
CA2 P00918 6/20 0.52
CA12 O43570 5/20 0.52
CA9 Q16790 5/20 0.52
CA7 P43166 4/20 0.52
CA3 P07451 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
KDM4E B2RXH2 1/20 0.51
SOS1 Q07889 3/20 0.49
LMNA P02545 1/20 0.47
PTGS2 P35354 2/20 0.46
TSHR P16473 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL3402419 0.98 ALDH1A1 (0.53) ALDH1A1HTTCA1CA2CA12
SCHEMBL972533 0.86 KDM4E (0.53) ALDH1A1HTTKDM4ELMNAPTGS2
SCHEMBL7994583 0.86 PTGS2 (0.56) ALDH1A1HTTKDM4ELMNAPTGS2
SCHEMBL3402420 0.84 ALDH1A1 (0.51) ALDH1A1HTTKDM4ELMNAPTGS2
SCHEMBL7993153 0.82 SMN1; SMN2 (0.60) ALDH1A1HTTCA1CA2CA12
SCHEMBL8737052 0.81 KDM4E (0.66) ALDH1A1HTTKDM4EMEN1KMT2A
SCHEMBL20988227 0.78 MAPT (0.61) ALDH1A1HTTLMNARAB9A
SCHEMBL14075565 0.78 SOS1 (0.61) ALDH1A1HTTCA1CA2CA12
SCHEMBL4598049 0.76 KDM4E (0.56) ALDH1A1HTTCA1CA2CA12
SCHEMBL20326546 0.76 KDM4E (0.43) ALDH1A1HTTKDM4ELMNAPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020200154-A1 A CLASS OF THIOPHENE FUSED N-HETEROCYCLIES, PREPARATION METHOD AND USE 上海凌达生物医药有限公司 2020-10-08 WO disclosed
US-20110015065-A1 Substituted Sulfonic Acid Amide Compounds BASF SE (DE) 2011-01-20 US disclosed
EP-2252590-A1 SUBSTITUTED SULFONIC ACID AMIDE COMPOUNDS BASF SE (DE) 2010-11-24 EP disclosed
WO-2009101082-A1 SUBSTITUTED SULFONIC ACID AMIDE COMPOUNDS BASF SE (DE) 2009-08-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015065-A1 Substituted Sulfonic Acid Amide Compounds STS, NAPA, NAAA ALDH1A1 2768/4885HTT 336/4885CA1 292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.