Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732936 | 0.90 | MAPT (0.54) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL9732943 | 0.87 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL9732575 | 0.87 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL9584018 | 0.79 | PLA2G2A (0.61) | ALDH1A1LMNA | |
| SCHEMBL9732159 | 0.77 | KDM4E (0.48) | ALDH1A1HTTLMNATDP1KMT2A | |
| SCHEMBL9732157 | 0.75 | PLA2G2A (0.49) | ALDH1A1SMN1; SMN2HTTLMNAKMT2A | |
| SCHEMBL9733084 | 0.73 | P2RX7 (0.52) | ALDH1A1HTTLMNATDP1KMT2A | |
| SCHEMBL29377589 | 0.73 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL1418988 | 0.73 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2HTTLMNATDP1 | |
| SCHEMBL28480601 | 0.73 | TDP1 (0.58) | ALDH1A1SMN1; SMN2HTTLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007829-A1 | INDOLE-3-METHANAMINES USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |