Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733084 | 0.89 | P2RX7 (0.52) | KDM4EKMT2AALDH1A1MAPTNTSR1 | |
| SCHEMBL9732157 | 0.89 | PLA2G2A (0.49) | KDM4EKMT2AALDH1A1MAPTNTSR1 | |
| SCHEMBL9733077 | 0.85 | ICMT (0.48) | KDM4EKMT2AALDH1A1MAPTNTSR1 | |
| SCHEMBL9731975 | 0.81 | P2RX7 (0.54) | KDM4EKMT2AALDH1A1MAPTNTSR1 | |
| SCHEMBL9734729 | 0.81 | PLA2G2A (0.43) | KDM4EKMT2AALDH1A1MAPTNTSR1 | |
| SCHEMBL9733317 | 0.79 | P2RX7 (0.52) | KDM4EKMT2AALDH1A1MAPTNTSR1 | |
| SCHEMBL9733238 | 0.77 | ALDH1A1 (0.52) | KDM4EKMT2AALDH1A1MAPTNTSR1 | |
| SCHEMBL9731969 | 0.77 | ICMT (0.50) | KDM4EKMT2AALDH1A1MAPTNTSR1 | |
| SCHEMBL9733154 | 0.77 | PLA2G2A (0.50) | KDM4EALDH1A1P2RX7PLA2G2AHTR6 | |
| SCHEMBL9734394 | 0.76 | MAPT (0.47) | MAPTLMNAP2RX7PLA2G2AICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007829-A1 | INDOLE-3-METHANAMINES USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |