Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAT2A | P31153 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733288 | 0.88 | ALDH1A1 (0.34) | ALDH1A1CYP2D6CYP2C19KDM4ELMNA | |
| SCHEMBL9734328 | 0.88 | ALDH1A1 (0.34) | ALDH1A1CYP2D6CYP2C19KDM4ELMNA | |
| SCHEMBL9733299 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP2D6CYP2C19KDM4ELMNA | |
| SCHEMBL9733681 | 0.83 | ALDH1A1 (0.45) | ALDH1A1CYP2D6CYP2C19KDM4ELMNA | |
| SCHEMBL9734002 | 0.81 | MALT1 (0.47) | ALDH1A1CYP2D6CYP2C19KDM4ELMNA | |
| SCHEMBL9733604 | 0.81 | ALDH1A1 (0.41) | ALDH1A1CYP2D6CYP2C19KDM4ELMNA | |
| SCHEMBL9733487 | 0.80 | MALT1 (0.39) | ALDH1A1CYP2D6CYP2C19KDM4ELMNA | |
| SCHEMBL9733850 | 0.80 | ALDH1A1 (0.41) | ALDH1A1CYP2D6CYP2C19KDM4ELMNA | |
| SCHEMBL9733292 | 0.79 | MEN1 (0.45) | ALDH1A1CYP2D6CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL9734163 | 0.79 | HIF1A (0.48) | ALDH1A1CYP2D6CYP2C19HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |