Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734163 | 0.93 | HIF1A (0.48) | MEN1KMT2AHIF1AALDH1A1TSHR | |
| SCHEMBL9733634 | 0.90 | ALDH1A1 (0.54) | MEN1KMT2AHIF1AALDH1A1SMN1; SMN2 | |
| SCHEMBL9733484 | 0.88 | MEN1 (0.48) | MEN1KMT2AHIF1AALDH1A1TSHR | |
| SCHEMBL9733681 | 0.87 | ALDH1A1 (0.45) | ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL9733574 | 0.86 | KMT2A (0.45) | MEN1KMT2AHIF1AALDH1A1RXFP1 | |
| SCHEMBL9734887 | 0.86 | MEN1 (0.47) | MEN1KMT2AHIF1AALDH1A1TSHR | |
| SCHEMBL9734053 | 0.86 | MEN1 (0.47) | MEN1KMT2AHIF1AALDH1A1TSHR | |
| SCHEMBL9733850 | 0.85 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL9733701 | 0.84 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL9734002 | 0.83 | MALT1 (0.47) | MEN1KMT2AALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | claimed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | claimed |
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |