Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734002 | 0.92 | MALT1 (0.47) | MALT1ALDH1A1CYP2D6CYP2C19KDM4E | |
| SCHEMBL9733850 | 0.90 | ALDH1A1 (0.41) | MALT1ALDH1A1CYP2D6CYP2C19KDM4E | |
| SCHEMBL9733701 | 0.88 | ALDH1A1 (0.47) | MALT1ALDH1A1CYP2D6CYP2C19KDM4E | |
| SCHEMBL9733604 | 0.88 | ALDH1A1 (0.41) | MALT1ALDH1A1CYP2D6CYP2C19KDM4E | |
| SCHEMBL9733681 | 0.88 | ALDH1A1 (0.45) | MALT1ALDH1A1CYP2D6CYP2C19KDM4E | |
| SCHEMBL9733424 | 0.86 | ALDH1A1 (0.44) | ALDH1A1CYP2D6CYP2C19KDM4EHPGD | |
| SCHEMBL9733299 | 0.86 | ALDH1A1 (0.47) | MALT1ALDH1A1CYP2D6CYP2C19KDM4E | |
| SCHEMBL9734019 | 0.82 | ALDH1A1 (0.59) | ALDH1A1CYP2D6CYP2C19KDM4ELMNA | |
| SCHEMBL9733685 | 0.82 | CA2 (0.41) | MALT1ALDH1A1CYP2D6CYP2C19KDM4E | |
| SCHEMBL9734163 | 0.82 | HIF1A (0.48) | ALDH1A1CYP2D6CYP2C19HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |