Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733424 | 0.96 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL9733850 | 0.94 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL9733681 | 0.90 | ALDH1A1 (0.45) | ALDH1A1CYP2C19CYP1A2CYP2C9CYP2D6 | |
| SCHEMBL9733487 | 0.88 | MALT1 (0.39) | ALDH1A1MEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL9733604 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL9734002 | 0.86 | MALT1 (0.47) | ALDH1A1MEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL9733299 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL9733292 | 0.84 | MEN1 (0.45) | ALDH1A1MEN1KMT2ACYP2C19CYP2D6 | |
| SCHEMBL9734019 | 0.82 | ALDH1A1 (0.59) | ALDH1A1CYP2C19CYP1A2CYP2C9CYP2D6 | |
| SCHEMBL9733685 | 0.82 | CA2 (0.41) | ALDH1A1KMT2ACYP2C19CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |