Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13840106 | 0.84 | NR1I2 (0.56) | L3MBTL1GAAHTTTP53TSHR | |
| SCHEMBL8787577 | 0.80 | L3MBTL1 (0.49) | L3MBTL1GAATP53TSHRPLA2G4B | |
| SCHEMBL1334249 | 0.78 | L3MBTL1 (0.58) | L3MBTL1GAAHTTTP53TSHR | |
| SCHEMBL9739233 | 0.77 | HTT (0.48) | L3MBTL1GAAHTTTP53TSHR | |
| SCHEMBL1334332 | 0.77 | L3MBTL1 (0.79) | L3MBTL1GAAMAPTLMNA | |
| SCHEMBL12321296 | 0.77 | L3MBTL1 (0.55) | L3MBTL1GAATP53TSHRPLA2G4B | |
| SCHEMBL19024978 | 0.77 | GAA (0.58) | L3MBTL1GAATP53TSHRMAPT | |
| SCHEMBL10548754 | 0.77 | MAPK1 (0.47) | L3MBTL1GAAHTTTP53TSHR | |
| SCHEMBL1925564 | 0.75 | PKM (0.67) | L3MBTL1HTTTP53TSHRPLA2G4B | |
| SCHEMBL27873175 | 0.75 | L3MBTL1 (0.53) | L3MBTL1GAATP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098613-A | Aromatic ethers for treatment of mammals | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |