Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM5A | P29375 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | CHUK | O15111 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29845683 | 0.86 | CYP1A2 (0.58) | CYP1A2GAALMNAALDH1A1MAPT | |
| SCHEMBL19984551 | 0.76 | KDM5A (0.67) | CYP1A2GAALMNAALDH1A1KDM5A | |
| SCHEMBL30474111 | 0.76 | KDM5A (0.67) | CYP1A2GAALMNAALDH1A1KDM5A | |
| SCHEMBL527043 | 0.73 | CYP1A2 (1.00) | CYP1A2GAALMNAALDH1A1MAPT | |
| SCHEMBL2464427 | 0.73 | DAO (0.53) | ALDH1A1MAPTHPGDKEAP1CHUK | |
| SCHEMBL16442084 | 0.72 | ALDH1A1 (0.72) | CYP1A2GAALMNAALDH1A1MAPT | |
| SCHEMBL26606899 | 0.72 | KIF11 (0.40) | ALDH1A1KDM5AMAPTHPGDPARP1 | |
| SCHEMBL19047346 | 0.71 | PARP1 (0.49) | ALDH1A1KDM5AHPGDPARP1CHUK | |
| SCHEMBL16650949 | 0.71 | KDM4E (0.58) | GAAKDM5AMAPTPARP1KDM4E | |
| SCHEMBL31338639 | 0.71 | PARP1 (0.49) | ALDH1A1KDM5AHPGDPARP1CHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230140413-A1 | Compounds and Methods for Treating, Detecting, and Identifying Compounds to Treat Apicomplexan Parasitic Diseases | THE UNIVERSITY OF CHICAGO | 2023-05-04 | — | — | US | disclosed |
| US-20230140413-A1 | Compounds and Methods for Treating, Detecting, and Identifying Compounds to Treat Apicomplexan Parasitic Diseases | THE UNIVERSITY OF CHICAGO | 2023-05-04 | — | — | US | disclosed |
| US-20200283391-A1 | Compounds and Methods for Treating, Detecting, and Identifying Compounds to Treat Apicomplexan Parasitic Diseases | THE UNIVERSITY OF CHICAGO | 2020-09-10 | — | — | US | disclosed |
| US-5126344-A | Angiotensin antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-30 | — | — | US | disclosed |
| EP-0454831-A1 | Diazine derivatives as angiotensin II receptor antagonists. | ICI PLC (GB) | 1991-11-06 | — | — | EP | disclosed |
| WO-1991007404-A1 | DIAZINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283391-A1 | Compounds and Methods for Treating, Detecting, and Identifying Compounds to Treat Apicomplexan Parasitic Diseases | TUBB1, MYADM, TUBB | CYP1A2 456/4885GAA 3214/4885LMNA 3310/4885 |
| US-20230140413-A1 | Compounds and Methods for Treating, Detecting, and Identifying Compounds to Treat Apicomplexan Parasitic Diseases | TUBB1, MYADM, TUBB | CYP1A2 504/4885GAA 2895/4885LMNA 3064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.