Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734968 | 0.87 | GAA (0.51) | GAAKDM4EMAPTMAPK1LMNA | |
| SCHEMBL9733677 | 0.82 | CA1 (0.53) | GAAKDM4EMAPTMAPK1TDP1 | |
| SCHEMBL9733717 | 0.79 | GAA (0.50) | GAAKDM4EMEN1KMT2A | |
| SCHEMBL9734162 | 0.78 | GAA (0.79) | GAAKDM4EMAPTMAPK1TDP1 | |
| SCHEMBL9734550 | 0.76 | KDM4E (0.53) | GAAKDM4ETDP1L3MBTL1MPO | |
| SCHEMBL9734499 | 0.76 | GAA (0.69) | GAAKDM4EMAPTMAPK1TDP1 | |
| SCHEMBL29274523 | 0.73 | GAA (0.66) | GAAKDM4ETDP1L3MBTL1MEN1 | |
| SCHEMBL29274529 | 0.72 | GAA (0.68) | GAAKDM4EMAPTMAPK1TDP1 | |
| SCHEMBL3833937 | 0.72 | PDE4A (0.48) | MAPK1 | |
| SCHEMBL3100738 | 0.71 | GAA (0.56) | GAAKDM4EMAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106975-A | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-04-21 | — | — | US | disclosed |