Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 11/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.73 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734499 | 0.94 | GAA (0.69) | GAAKDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL9736223 | 0.87 | ALDH1A1 (0.61) | GAAKDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL9734968 | 0.80 | GAA (0.51) | GAAKDM4EMAPTMAPK1 | |
| SCHEMBL3381072 | 0.80 | GAA (0.77) | GAAKDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL9212536 | 0.79 | GAA (0.71) | GAAKDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL10899727 | 0.79 | GAA (0.71) | GAAKDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL9733548 | 0.78 | GAA (0.50) | GAAKDM4EMAPTTDP1MAPK1 | |
| SCHEMBL9733717 | 0.78 | GAA (0.50) | GAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9734929 | 0.77 | KDM4E (0.51) | GAAKDM4EMAPTALDH1A1TDP1 | |
| SCHEMBL8843603 | 0.77 | GAA (0.64) | GAAKDM4EMAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106975-A | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0434185-A2 | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-06-26 | — | — | EP | disclosed |