Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733548 | 0.87 | GAA (0.50) | GAAKDM4EMPOMAPTMEN1 | |
| SCHEMBL9733717 | 0.80 | GAA (0.50) | GAAKDM4EALOX5MEN1KMT2A | |
| SCHEMBL9734162 | 0.80 | GAA (0.79) | GAAKDM4EMAPTMAPK1 | |
| SCHEMBL9734499 | 0.77 | GAA (0.69) | GAAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL9734550 | 0.77 | KDM4E (0.53) | GAAKDM4EMPOMEN1KMT2A | |
| SCHEMBL9735255 | 0.76 | KDM4E (0.47) | GAAKDM4EMPOMAPTLMNA | |
| SCHEMBL29274523 | 0.75 | GAA (0.66) | GAAKDM4EMEN1KMT2A | |
| SCHEMBL29274529 | 0.74 | GAA (0.68) | GAAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL13572662 | 0.74 | MEN1 (0.53) | GAAKDM4EMEN1KMT2A | |
| SCHEMBL3100738 | 0.72 | GAA (0.56) | GAAKDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106975-A | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0434185-A2 | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-06-26 | — | — | EP | disclosed |