Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 3/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734049 | 0.86 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL9733998 | 0.82 | EGFR (0.46) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL9733265 | 0.73 | ATM (0.48) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL4519168 | 0.72 | KMT2A (0.48) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL4521552 | 0.72 | MEN1 (0.64) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL10973972 | 0.72 | CNR1 (0.57) | ALDH1A1KMT2ALMNAHPGDGAA | |
| SCHEMBL9732906 | 0.70 | ALDH1A1 (0.54) | ALDH1A1KMT2ALMNAHPGDGAA | |
| SCHEMBL4506234 | 0.70 | KMT2A (0.76) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL9733130 | 0.69 | HTR1A (0.43) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL11075597 | 0.69 | CNR1 (0.56) | ALDH1A1KMT2ALMNAHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |