Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | GAK | O14976 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734049 | 0.85 | ALDH1A1 (0.49) | TSHRHIF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL9733998 | 0.83 | EGFR (0.46) | TSHRGAKMEN1KMT2AALDH1A1 | |
| SCHEMBL9734041 | 0.83 | ALDH1A1 (0.51) | HTR1AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9733484 | 0.81 | MEN1 (0.48) | TSHRHIF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL9734887 | 0.79 | MEN1 (0.47) | TSHRHIF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL9734053 | 0.79 | MEN1 (0.47) | TSHRHIF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL9733292 | 0.77 | MEN1 (0.45) | TSHRHIF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL9733564 | 0.69 | ALDH1A1 (0.52) | TSHRMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9734163 | 0.69 | HIF1A (0.48) | TSHRHIF1AMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9733337 | 0.69 | HIF1A (0.38) | HTR1AHTR7TSHRHIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | claimed |
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |