Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | GAK | O14976 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733130 | 0.83 | HTR1A (0.43) | EGFRGAKPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9733564 | 0.82 | ALDH1A1 (0.52) | POLBALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL9732906 | 0.77 | ALDH1A1 (0.54) | POLBALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL734003 | 0.76 | PIK3CD (0.61) | POLBALDH1A1CYP2D6CYP2C19LMNA | |
| SCHEMBL9733265 | 0.75 | ATM (0.48) | POLBALDH1A1CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL734149 | 0.75 | PIK3CG (0.54) | POLBALDH1A1CYP2D6CYP2C19LMNA | |
| SCHEMBL733963 | 0.71 | PIK3CG (0.58) | POLBALDH1A1CYP2D6CYP2C19LMNA | |
| SCHEMBL1261561 | 0.71 | PIK3CD (0.46) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL733511 | 0.71 | PIK3CD (0.61) | ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL4393532 | 0.70 | ALDH1A1 (0.63) | POLBALDH1A1CYP2D6CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |