Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPRG | P23470 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28508835 | 0.80 | MAOA (0.42) | ALDH1A1PTPRCPTPRGDGAT1CES2 | |
| SCHEMBL3198739 | 0.80 | PTPRC (0.50) | PTPRCPTPRGPOLBKMT2AMEN1 | |
| SCHEMBL3473049 | 0.79 | ALDH1A1 (0.50) | GAAALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL22246813 | 0.79 | DGAT1 (0.55) | ALDH1A1PTPRCPTPRGDGAT1CES2 | |
| SCHEMBL6174178 | 0.78 | HSP90AB1 (0.48) | HSP90AB1GAATHRATHRBALDH1A1 | |
| SCHEMBL1922044 | 0.77 | HSP90AB1 (0.47) | HSP90AB1GAAPOLBDGAT1LMNA | |
| SCHEMBL7534898 | 0.77 | HSP90AB1 (0.67) | HSP90AB1GAAALDH1A1POLBLMNA | |
| SCHEMBL30863507 | 0.77 | HSP90AB1 (0.67) | HSP90AB1GAAALDH1A1POLBLMNA | |
| SCHEMBL14799647 | 0.77 | HSP90AB1 (0.47) | HSP90AB1GAAALDH1A1POLBDGAT1 | |
| SCHEMBL17504939 | 0.76 | NR4A2 (0.49) | GAAALDH1A1POLBL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135940-A | Antiallegens, antiinflammatory agents | MERCK FROSST CANADA, INC. (CA) | 1992-08-04 | — | — | US | disclosed |
| EP-0252639-A1 | Leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1988-01-13 | — | — | EP | disclosed |