Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 7/20 | 0.41 |
| ▸ | GLA | P06280 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734073 | 0.83 | ALDH1A1 (0.61) | KDM4EMPOMETAP2NPC1ALDH1A1 | |
| SCHEMBL9733848 | 0.82 | HPGD (0.48) | KDM4EMPONPC1ALDH1A1LMNA | |
| SCHEMBL9733496 | 0.77 | KDM4E (0.47) | KDM4EMPOALDH1A1LMNAHTT | |
| SCHEMBL9733705 | 0.77 | ALDH1A1 (0.62) | KDM4EMPOMETAP2NPC1ALDH1A1 | |
| SCHEMBL9734058 | 0.73 | ALDH1A1 (0.56) | KDM4EMPOALDH1A1LMNAHTT | |
| SCHEMBL3210905 | 0.72 | ALDH1A1 (0.69) | KDM4EMETAP2NPC1ALDH1A1LMNA | |
| SCHEMBL7064678 | 0.71 | ALDH1A1 (0.68) | KDM4EMETAP2NPC1ALDH1A1LMNA | |
| SCHEMBL9733707 | 0.71 | KDM4E (0.43) | KDM4EMPOALDH1A1LMNAGAA | |
| SCHEMBL9734834 | 0.70 | MAPT (0.48) | KDM4EMPOALDH1A1LMNAGAA | |
| SCHEMBL9735204 | 0.70 | KDM4E (0.47) | KDM4EMPOALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106975-A | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0434185-A2 | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-06-26 | — | — | EP | disclosed |