Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 15/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.48 |
| ▸ | CASP7 | P55210 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733496 | 0.83 | KDM4E (0.47) | HPGDHIF1AKMT2APOLBMEN1 | |
| SCHEMBL9733716 | 0.82 | KDM4E (0.47) | HPGDHIF1AHSD17B10CASP7KMT2A | |
| SCHEMBL9733707 | 0.80 | KDM4E (0.43) | HPGDHIF1AHSD17B10CASP7KMT2A | |
| SCHEMBL9734073 | 0.79 | ALDH1A1 (0.61) | HPGDHIF1AHSD17B10KMT2APOLB | |
| SCHEMBL9734031 | 0.78 | KDM4E (0.42) | HPGDHIF1AHSD17B10CASP7KMT2A | |
| SCHEMBL9734014 | 0.75 | KDM4E (0.42) | HPGDHIF1AHSD17B10KMT2APOLB | |
| SCHEMBL9734077 | 0.73 | GAA (0.41) | HPGDHIF1AHSD17B10KMT2APOLB | |
| SCHEMBL9733705 | 0.73 | ALDH1A1 (0.62) | HSD17B10POLBMAPTTSHRMAPK1 | |
| SCHEMBL9733734 | 0.73 | ALDH1A1 (0.64) | HPGDHIF1AHSD17B10POLBMAPT | |
| SCHEMBL9733787 | 0.71 | GAA (0.42) | HPGDHIF1AHSD17B10KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106975-A | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0434185-A2 | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-06-26 | — | — | EP | disclosed |