Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.38 |
| ▸ | HPGD | P15428 | 9/20 | 0.38 |
| ▸ | GAA | P10253 | 9/20 | 0.38 |
| ▸ | GLA | P06280 | 8/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734031 | 0.90 | KDM4E (0.42) | KDM4EMPOALDH1A1HPGDGAA | |
| SCHEMBL9733848 | 0.80 | HPGD (0.48) | KDM4EMPOALDH1A1HPGDGAA | |
| SCHEMBL9733787 | 0.73 | GAA (0.42) | KDM4EMPOALDH1A1HPGDGAA | |
| SCHEMBL9734077 | 0.72 | GAA (0.41) | KDM4EMPOALDH1A1HPGDGAA | |
| SCHEMBL9733716 | 0.71 | KDM4E (0.47) | KDM4EMPOALDH1A1HPGDGAA | |
| SCHEMBL9733496 | 0.71 | KDM4E (0.47) | KDM4EMPOALDH1A1HPGDGAA | |
| SCHEMBL9734834 | 0.63 | MAPT (0.48) | KDM4EMPOALDH1A1HPGDGAA | |
| SCHEMBL8641590 | 0.63 | TSHR (0.56) | ALDH1A1HPGDGLAHIF1AMAPT | |
| SCHEMBL9734929 | 0.63 | KDM4E (0.51) | KDM4EMPOALDH1A1GAAMAPT | |
| Pentachlorophenol SCHEMBL5845375 | 0.62 | TSHR (0.77) | ALDH1A1HPGDGLAHIF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106975-A | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-04-21 | — | — | US | disclosed |