Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DBH | P09172 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733705 | 0.88 | ALDH1A1 (0.62) | KDM4EPOLBSMN1; SMN2DBHALDH1A1 | |
| SCHEMBL6568587 | 0.87 | POLB (0.62) | KDM4EPOLBSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9733734 | 0.85 | ALDH1A1 (0.64) | KDM4EPOLBSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9733848 | 0.83 | HPGD (0.48) | KDM4EPOLBSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9734929 | 0.78 | KDM4E (0.51) | KDM4EALDH1A1GAATDP1MPO | |
| SCHEMBL9734073 | 0.77 | ALDH1A1 (0.61) | KDM4EPOLBALDH1A1GAATDP1 | |
| SCHEMBL9733716 | 0.77 | KDM4E (0.47) | KDM4EPOLBSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9734058 | 0.77 | ALDH1A1 (0.56) | KDM4EPOLBALDH1A1GAATDP1 | |
| SCHEMBL9734743 | 0.75 | KDM4E (0.45) | KDM4ESMN1; SMN2DBHALDH1A1GAA | |
| SCHEMBL9733983 | 0.74 | MAPT (0.65) | KDM4EALDH1A1GAATDP1MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106975-A | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0434185-A2 | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-06-26 | — | — | EP | disclosed |