Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | GLA | P06280 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734077 | 0.90 | GAA (0.41) | GAAKDM4EMPOALDH1A1GLA | |
| SCHEMBL10030555 | 0.78 | GAA (0.44) | GAAKDM4EMPOALDH1A1MEN1 | |
| SCHEMBL9734014 | 0.77 | KDM4E (0.42) | GAAKDM4EMPOALDH1A1GLA | |
| SCHEMBL9733707 | 0.73 | KDM4E (0.43) | GAAKDM4EMPOALDH1A1GLA | |
| SCHEMBL9735204 | 0.73 | KDM4E (0.47) | GAAKDM4EMPOALDH1A1GLA | |
| SCHEMBL9735881 | 0.73 | KDM4E (0.47) | GAAKDM4EMPOALDH1A1GLA | |
| SCHEMBL9734031 | 0.72 | KDM4E (0.42) | GAAKDM4EMPOALDH1A1GLA | |
| SCHEMBL9733848 | 0.71 | HPGD (0.48) | GAAKDM4EMPOALDH1A1GLA | |
| SCHEMBL9734929 | 0.69 | KDM4E (0.51) | GAAKDM4EMPOALDH1A1MEN1 | |
| SCHEMBL10030554 | 0.68 | GAA (0.47) | GAAKDM4EALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106975-A | Hexahydropyrimidine derivatives | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-04-21 | — | — | US | disclosed |