Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26424875 | 0.76 | HPGD (0.66) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL31701605 | 0.75 | MAPT (0.66) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL17988255 | 0.75 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL9733812 | 0.69 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL27075492 | 0.69 | HSD17B10 (0.67) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL29714590 | 0.69 | HSD17B10 (0.71) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL31701624 | 0.69 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL9732938 | 0.69 | MAPT (0.78) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL5322140 | 0.68 | CASP1 (0.57) | ALDH1A1HPGDLMNASMN1; SMN2TSHR | |
| SCHEMBL31702048 | 0.68 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124331-A | Anticancer agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0364598-A1 | 3,4-dihydrothieno ¬2,3-d pyrimidine compounds and pharmaceutical application thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-25 | — | — | EP | disclosed |